KQ8 Organization anywhere between dietary potassium intake and you can heart disease, cardiovascular system problem, stroke, kidney situation, and you may death
Lookup Means: “Potassium, Dietary”[Mesh] Or potassium[tiab] Otherwise KLOR-CON[tiab] Or KCL[tiab] And “Cardio Infection”[Mesh] Or cardiovascular illnesses*[tiab] Or acute coronary problem* [tiab] Or “erratic angina” Or myocardial infarct* Or heart attack Or strokes Or “center incapacity” Otherwise “cardiovascular disease” Otherwise kidney mode* Otherwise kidney situation*[tiab] Or “creatinine approval” Otherwise “gel creatinine” Otherwise albuminuria Or proteinuria Otherwise “glomerular filtration” Otherwise “end phase kidney problem”[tiab] Or “Kidney Illness”[Mesh] Or persistent renal condition*[tiab] Or “albumin-to-creatinine ratio” Or “albumin so you’re able to creatinine ratio” Otherwise kidney brick* Otherwise serious kidney injur* Or “renal calculi” Otherwise renal lithiasis Otherwise nephrolith* Or nephrolithiasis Otherwise renal brick Or kidney calculi Or “Mortality”[Mesh] Otherwise mortality[sh] Or death[tiab] And you can “Possible Degree”[Mesh]) Or “Case-Handle Studies”[Mesh:NoExp] Or “potential cohort” Otherwise “nested instance-control” Otherwise “metabolic studies” Or try*[tiab] Otherwise clinical test* And humans[MESH] Otherwise ((inprocess[sb] Otherwise writer[sb] Or pubmednotmedline [sb]) Perhaps not (mice[ti] Otherwise mouse[ti] Or rats[ti] Or pet[ti]))
Along with resource mining Aburto ainsi que al., 2013 36 ; Dickinson ainsi que al., 2006 38 ; NHLBI, 2013 5 ; Beyer mais aussi al., 2006 39 ; DRI report; or other logical ratings recognized on scoping research.
The brand new important endpoint picked getting devotion of your own Bearable Upper Intake Level (UL) is actually blood circulation pressure. 2 The latest IOM concluded that the partnership ranging from salt intake and you will blood pressure level try continuous instead of an apparent tolerance which means that they are difficult to truthfully put a beneficial UL, particularly since the other variables (lbs, take action, potassium intake, weightloss trend, alcoholic drinks consumption, and you may hereditary circumstances) also apply at blood pressure level. The fresh feabie com gratis proefversie IOM set the UL to have salt within 2,3 hundred milligrams a-day for all of us old fourteen ages and over, having all the way down beliefs of these step 1-13 yrs . old. Inside dosage-effect samples, which level is actually aren’t the next level above the AI one to is actually checked. The fresh ULs for children was extrapolated regarding the adult UL situated to the average energy consumption. It should be detailed the UL is not an elective consumption and, as with other ULs, there isn’t any advantage to ingesting profile above the AI. step 1
II. The main Inquiries
Because of the great number of established input education of salt cures and potassium while the viability and robustness of the RCT construction to assess the outcome of treatments, we shall restrict KQ step 1, 3, 5, and seven so you can RCTs. Good review methods might be selected also enter in regarding Technology Expert Committee (TEP) and you may stuff professional help this health-related review.
E. Investigation Synthesis
Possible Fellow Reviewers need to disclose people monetary issues of great interest better than $ten,000 and just about every other related team otherwise elite issues of great interest. Greeting Peer Writers might not have any financial argument of great interest greater than $10,100. Fellow writers who disclose potential team otherwise elite disputes of interest get submit statements on draft records from the social comment device.]]
And additionally reference mining Aburto ainsi que al., 2013 twenty-four ; Adler et al., 2014 29 ; Johnson mais aussi al., 2015 25 ; McMahon et al., 2015 29 , Poggio et al., 2015 thirty-two ; Graudal mais aussi al., 2014 33 ; Suckling ainsi que al., 2010 34 ; Stazzullo mais aussi al., 2009 35 ; DRI statement; or other health-related reviews understood about scoping look
Plus reference mining Aburto ainsi que al., 2013 thirty-six ; Dickinson ainsi que al., 2006 38 ; NHLBI, 2013 5 ; DRI declaration; or other health-related ratings identified on scoping look
- Within the provided degree not revealing into prespecified consequences: one study-specific blood circulation pressure scale
- Kidney stone frequency
- He FJ, Li J, Macgregor GA. Effect of prolonged-title small sodium avoidance towards blood circulation pressure. Cochrane Databases Syst Rev. 2013;4(1469-493X (Electronic)):Cd004937. doi: 1858.CD004937.pub2. PMID: 23633321.
- McMahon EJ, Campbell KL, Bauer JD, et al. Altered diet salt intake for those who have chronic kidney condition. Cochrane Database Syst Rev. 2015(2):CD010070. doi: 1858.CD010070.pub2. PMID: 25691262.